Electronic Records and Signatures

21 CFR Part 11 LIMS Software for Controlled Electronic Records

LabZila provides configurable controls for managing electronic laboratory records, user access, audit histories, reviews and electronic signatures. Connect these controls with samples, testing, quality processes, equipment and reporting while maintaining clear accountability throughout each regulated workflow.

Controlled User Access Traceable Audit History Electronic Review and Signatures

Core Features of LabZila 21 CFR Part 11 LIMS Software

Support controlled electronic records, traceable approvals and accountable laboratory workflows through configurable system controls.

Controlled Electronic Records

Create, review and maintain laboratory records with defined statuses, permissions and complete activity histories.

Electronic Signatures

Capture authorised electronic approvals with signer identity, date, time and configured signature meaning.

Audit Trail History

Record applicable changes, actions, comments and approvals with user attribution and timestamps.

Role-Based Access Control

Limit record access and system actions according to each user’s assigned role and responsibilities.

Review and Approval Workflows

Route records through technical review, correction, approval and authorisation stages.

Record Retention and Retrieval

Maintain searchable electronic records and retrieve authorised copies throughout configured retention periods.

Validation and Change Control

Support intended-use testing, controlled configuration changes and documented system-review activities.

Data Integrity Controls

Keep samples, results, methods, signatures and record histories connected for clearer traceability.

Control Electronic Records from Creation to Retention

Manage laboratory records through controlled access, traceable activity, authorised review and electronic approval.

1

Create Record

An authorised user creates or updates the required electronic laboratory record.

2

Apply Controls

Required fields, permissions and workflow stages guide the record through the approved process.

3

Record Activity

Applicable entries, changes and actions are captured with user attribution and timestamps.

4

Review and Sign

Qualified personnel review the record and apply the required electronic approval or signature.

5

Preserve History

Audit history retains applicable changes, comments, approvals and signature activity.

6

Finalise and Retain

The approved record is finalised and remains available for authorised retrieval and retention.

Why Choose LabZila for Part 11 Workflows?

LabZila provides configurable controls for electronic records, signatures, user access and approval workflows across connected laboratory processes. These capabilities can support a laboratory’s Part 11 approach when combined with appropriate validation, procedures, training and governance.

Role-based access and user accountability
Time-stamped record and approval histories
Electronic signatures with clear signing meaning
Controlled review and authorization workflows
Searchable electronic records and activity history
Validation and change-control support
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Part 11 Support for Applicable Laboratory Workflows

LabZila provides configurable controls for electronic records, signatures, user access and activity histories across laboratory environments. Part 11 applicability depends on whether FDA-required records are maintained electronically or electronic signatures replace handwritten signatures under the relevant predicate rules.

Pharma QC

  • Controlled test and batch records
  • Electronic reviews and signatures
  • Traceable change and approval history
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Clinical Diagnostics

  • Applicable regulated electronic records
  • Role-based review and authorization
  • Searchable signature and activity history
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Environmental Testing

  • Controlled records for regulated projects
  • Result review and approval workflows
  • Time-stamped record histories
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Food & Beverage Testing

  • Applicable FDA electronic records
  • Controlled approvals and signatures
  • Traceable changes and retention
Explore Food Testing LIMS

Cannabis Testing

  • Controlled sample and result records
  • Role-based review workflows
  • Complete approval and activity history
Explore Cannabis Testing LIMS

Contract Research

  • Client-specific regulated workflows
  • Electronic signatures and approvals
  • Controlled record retention and retrieval
Explore Contract Research LIMS

Benefits of LabZila for Part 11 Workflows

Strengthen Record Control

Manage electronic records through defined access, review, approval and retention controls.

Improve Data Integrity

Maintain user-attributed, time-stamped and traceable histories of applicable record activity.

Support Electronic Approvals

Capture reviewer identity, signature date, time and approval meaning within the relevant record.

Reduce Manual Follow-Up

Automate assignments, reminders and approval routing across configured laboratory workflows.

Simplify Inspection Preparation

Retrieve electronic records, audit histories, signatures and supporting evidence from one connected system.

Common Questions

Frequently Asked Questions

What is 21 CFR Part 11 LIMS software?

A 21 CFR Part 11 LIMS is laboratory software that provides controls for electronic records and electronic signatures used in applicable FDA-regulated workflows. These controls may include restricted access, audit trails, electronic approvals, record protection and authorised retrieval.

Does using LabZila automatically make our laboratory Part 11 compliant?

No. LabZila can provide configurable technical controls that support a laboratory’s Part 11 approach, but compliance also depends on determining which records are in scope, validating the configured system, maintaining approved procedures, training users and governing access and signatures appropriately.

Which electronic laboratory records may fall under Part 11?

Part 11 generally applies when records required by FDA regulations are created, modified, maintained, archived, retrieved, transmitted or submitted electronically. Applicability depends on the relevant FDA predicate rule and how the laboratory uses the electronic system.

Does LabZila support electronic signatures?

LabZila can support configured electronic review and signature workflows for authorised users. Applicable signed records should identify the signer, record the signing date and time and state the meaning of the signature, such as review, approval, responsibility or authorship.

How does LabZila support audit trails?

LabZila can maintain time-stamped histories of applicable record creation, changes, actions, reviews and approvals. Part 11 closed-system controls call for computer-generated audit trails that preserve previously recorded information and remain available for authorised review.

Does a 21 CFR Part 11 LIMS need to be validated?

A laboratory should validate the configured system according to its intended use and applicable requirements. Part 11 closed-system controls include validation to support accuracy, reliability, consistent intended performance and the ability to identify invalid or altered records.

Can electronic records be retrieved for inspections or reviews?

Part 11 controls include protecting records throughout their required retention period and producing accurate, complete copies in human-readable and electronic formats suitable for authorised inspection, review and copying. LabZila can support searchable record access and retrieval according to its confirmed configuration.

Who is responsible for maintaining Part 11 compliance?

Compliance is a shared responsibility. LabZila can provide technical controls for access, records, signatures and workflows, while the laboratory remains responsible for applicability assessments, validation, authorised roles, SOPs, training, retention policies and ongoing system governance.

Strengthen Electronic Record Control

Ready to Support Your 21 CFR Part 11 Workflows?

See how LabZila can help your laboratory manage electronic records, audit histories, role-based access, controlled approvals and electronic signatures within one configurable LIMS.